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技術紹介

BMG LABTECH 社のプレートリーダーには、最先端でユニークな光学技術を用いています。
また、この技術革新の多くはお客様からのご要望に対応するべく行われています。つまり、お客様が我々の技術革新と技術の向上の原動力なのです。

測定技術

 

ハイエンドTRFオプション

Advanced TRF Optic Head

自動化

Automation

消光モニタリング

Decay Curve Monitoring

高感度発光測定

Dedicated high performance luminescence

二波長完全同時測定

Simultaneous Dual Emission

下方測定

Direct Optic bottom reading

ガスパージ

Gas vent

温度制御/シェイキング

Incubation/Shaking

LVF式モノクロメーター

Linear Variable Filter (LVF) Monochromators

光学モジュール

Optic Modules

光路長補正機能

Path length correction

PHERAstar 光学系

PHERAstar detection system

試薬ディスペンサ

Reagent injectors

タンデムテクノロジー

Tandem Technology

TR-FRET用UVレーザー

UV Laser for TR-FRET Assays

UV/Vis スペクトロメーター

UV/Vis spectrometer

ウェルスキャニングモード

Well scanning modes

Z軸方向の最適化

Z-Height Focus

  

  

測定方法

  

蛍光測定(FRET含む)

Fluorescence Intensity(Including FRET)

偏光蛍光測定

Fluorescence Polarization

発光測定(BRET含む)

Luminescence (Including BRET) 

吸光度測定

Absorbance

時間分解蛍光測定

Time-Resolved Fluorescence

TR-FRET

TR-FRET

AlphaScreen® mode

AlphaScreen® mode

光散乱測定

Nephelometry

  

 

アッセイテクノロジー

  

  

  

BMG blog バックナンバー

Monday, June 2, 2014

Experimental drug could be useful MERS treatment

MERS (Middle Eastern Respiratory Syndrome) has been featured in the news of late due to the spread of the disease globally.

詳しくはこちらから

Wednesday, December 18, 2013 

Advanced Spectroscopy Technique Allows Scientists to Analyze Protein Structure with Infrared Light

Proteins come in many forms and are essential for cellular function. Each protein has a defined structure that is necessary for the protein to perform its function. The most common structures found in proteins are alpha helices and beta pleated sheets. Disruption of the normal common structures in a protein is associated with diseases such as Alzheimer or Parkinsons disease.

詳しくはこちらから

Tuesday, December 17, 2013

Newly Discovered Regulation of KRas may Result in Novel Cancer Therapies

KRas has been well characterized for its role in several cancers. Mutations of KRas are seen in more than 90% of pancreatic cancer patients, and are prevalent in colon and lung cancer. However, targeting KRas for cancer therapy has been difficult.

詳しくはこちらから

Monday, December 16, 2013

Scientists study essential enzyme to better understand molecular evolution

Scientists at the University of Iowa analyzed various forms of the enzyme dihydrofolate reductase (DHFR) using bioinformatics, computer-based calculations, artificial mutagenesis and kinetic measurements. The result of their work is published in the recent JBC paper entitled: 'Preservation of Protein Dynamics in Dihydrofolate Reductase Evolution'.

詳しくはこちらから

Wednesday, November 27, 2013

Scientists now able to observe molecular motor movement during cell division

The molecular motor Xkid is well characterized for its critical role in aligning chromosomes during cell division. This has been determined based on results obtained from in vitro experiments using purified Xkid, which showed directed movement of this protein on microtubules. However, until now scientists had not been able to observe Xkid behavior on intact spindles.

詳しくはこちらから

Tuesday, November 26, 2013

Two separate studies identify new potential AML treatments

AML, or acute-myeloid leukemia is a cancer characterized by rapid growth of abnormal blood cells. AML is a disease that is actually characterized by a wide range of diversity in terms of genetics. A genetic hallmark of about 10% of AML is mutation of epigenetic repression or C/EBPα. Two separate studies have investigated AML with C/EBPα dysfunction and found two separate potential targets for treatment. Both studies represent the work of international collaborations.

詳しくはこちらから

Monday, November 25, 2013

X-ray laser protein modeling may be useful for solving membrane protein structures

Membrane proteins, such as G-protein coupled receptors and receptor tyrosine kinases, are well characterized for their role in important cellular functions and represent the major targets for new drug development. However, only a small fraction of membrane proteins have had their three dimensional structure completely mapped by traditional techniques. This lack of structural information is due, in large part, to the inability to obtain large crystals of pure membrane proteins.

詳しくはこちらから

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